Southampton, Jan. 17 -- Derby came from two goals down for the second time against Southampton to eliminate the Premier League club from the FA Cup on Wednesday, winning a penalty shootout following a 2-2 draw in their third-round replay.

Derby captain Richard Keogh converted the decisive spot kick to secure a 5-3 win in the shootout after Nathan Redmond missed the only penalty for Southampton by shooting wide.

Southampton, which also led 2-0 in the teams' first 2-2 draw on Jan. 5, looked to be headed for the fourth round after Stuart Armstrong and Redmond scored in the 68th and 70th minutes to put the Premier League side in control. But Harry Wilson pulled one back with a free kick in the 76th and Martyn Waghorn equalized six minutes l...