Singapore, April 22 -- South Korea's biotechnology company Hyundai Bioscience has completed the development of a niclosamide-based formulation to treat dengue fever with a drug concentration level at or above 50% viral inhibition (IC50), which can also work on Zika, Chikungunya, and Yellow fever viruses.

Despite niclosamide's broad-spectrum antiviral activity, researchers failed to develop niclosamide-based antivirals due to its low absorption and short half-life. Hyundai Bioscience tackled the challenges with bio-friendly inorganic substances and polymers based on its proprietary drug delivery system (DDS) technology.

The company would carry out global clinical tests aimed at treating all serotypes of dengue virus infection.

"The fund...